The Medicine Maker has spent 10 years publishing interviews, articles and commentary covering the entire spectrum of drug development and manufacturing. Here, we look back on the field of advanced medicine. Cell and gene therapies have seen incredible progress over the past decade, including the approval of the world’s first approved CAR T therapy. We celebrate the achievements of the field by taking a look at some of our top articles.
A Guiding Light for CRISPR
The story of how Caribou Biosciences developed a hybrid RNA-DNA guide to increase Cas9 specificity – and what the name of the technology has got to do with the Burgundy wine region in France…
Memories From the Start of the Gene Therapy Wave: Lessons Learned with Alan Boyd
The remarkable story of gene therapy drug development during the 1990s and early 2000s
TILs Taking on Solid Tumors
Looking into the development of Amtagvi – the world’s first approved T-cell therapy for a solid tumor
Cell and Gene 4.0
May the fourth industrial revolution be with you…
Advanced – But Not Advanced Enough
Great successes are being seen in gene therapy, but there are still gaps in our scientific knowledge – and our manufacturing prowess
Less Than 5 Percent Human Effort: Thoughts on the Role of Automation on Cell and Gene Therapy
We all know that automation can reduce human labor, but how else can it make economically viable cell and gene therapies a reality?
Titan on the Horizon
Mammoth-resurrection company Colossal has spawned a digital pharma entity that wants to take cell and gene therapy to its next stage of evolution
Weathering the Storm: Cell and Gene’s Economic Downturn
An early wave of investor enthusiasm followed by an economic crisis has landed our field in a sea of trouble – so how can we swim to shore?
Dreaming of an Efficient Future
The rapid rise of cell and gene therapies took the industry by surprise. We know these therapies can be commercialized; but to do so efficiently, we must turn our attention to new challenges, including optimized manufacturing strategies and streamlined patient access.
Of Plumbing and Poetry
Sitting Down With… Sandy Macrae, Chief Executive Officer, Sangamo Therapeutics, USA
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