The Medicine Maker

In this issue, Upfront covers resilient supply chains, vaccine wars, and a gene therapy showing remarkable results in paralyzed animals. The focus of our cover feature is COVID-19; we gather experts from different sectors of the pharma industry to discuss how the pandemic has affected leadership and communication. Also in this issue: Ewoud van Tricht discusses analytical methods for vaccines, Alice Dunbabin talks about the benefits of biocatalysts; and Angela Myers and Michael Lehmicke explain how to standardize advanced therapy manufacture. We also have an interview with Sandy Macrae, CEO of Sangamo.

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Business & Regulation Cell & Gene Development & Clinical Outsourcing Technology & Manufacturing Formulation Regulation & Standards Supply Chain Business & Trends

Leadership in Times of Crisis

March 4, 2021

At the CPhI Festival of Pharma held in 2020, The Medicine Maker held a roundtable discussion featuring members of our previous Power Lists to discuss the challenges of leadership during these trying times. Below is an excerpt from the discussion. You can watch the full video at: tmm.txp.to/covid19video

1 min read

Business & Regulation Business & Trends Small Molecules

COVID-19: A Year of Unprecedented Change

March 1, 2021

All eyes have been on the pharmaceutical industry throughout 2020 – assessing its capacity to provide an answer to a truly global challenge. Here, experts from across the industry share their views on the challenges the small molecule sector has faced – and the sector’s outlook for 2021.

1 min read

COVID-19: A Year of Unprecedented Change

Manufacture Regulation & Standards Business & Trends

How to Standardize Advanced Therapy Manufacture

February 20, 2021

Cell and gene therapy manufacturing technologies and methods are advancing rapidly, but can regulators keep up? Given the uniqueness of each product, what will it take to make high standards and best practices a reality across the board?

1 min read

How to Standardize Advanced Therapy Manufacture

Discovery & Development Drug Delivery

Painting the Future of Drug Delivery

February 19, 2021

US Army combat veteran Luis Alvarez has developed a new drug delivery technology that can convert any recombinant protein into a material-binding variant. Here, we find out how the tech can help coat implants and enable long-term local delivery.

1 min read

Business & Regulation Business & Trends

Big Pharma: Heal Thyself

February 9, 2021

Pharma hasn’t always covered itself in glory – but as the world scrambles for viable COVID-19 interventions, it has a rare opportunity to rebrand

1 min read

Manufacture Small Molecules Formulation Outsourcing Technology & Manufacturing

Are You a Bio-Catalytic Converter?

February 9, 2021

Speed and efficiency are everything in pharmaceutical synthesis – and that’s why biocatalysis is an increasingly attractive option

1 min read

Discovery & Development Formulation Drug Delivery

Crossing the Border

February 8, 2021

How to get macromolecules across the intestinal epithelial barrier

1 min read

Discovery & Development Formulation Drug Delivery Sponsored

The Inhalation Advantage

February 4, 2021

Faster and more affordable development of inhaled medicines

1 min read

Manufacture Bioprocessing Biopharma Facilities & Equipment Technology & Manufacturing Sponsored

Capturing Value in Changing Times

February 4, 2021

The increasing complexity of biologics raises significant manufacturing challenges – not least regarding cost control and downstream purification. Thermo Fisher Scientific’s answer? To boost capture efficiency with a scalable, broadly applicable platform technology called CaptureSelect (TM).

1 min read

Manufacture Cell & Gene

Of Plumbing and Poetry

February 4, 2021

Sitting Down With… Sandy Macrae, Chief Executive Officer, Sangamo Therapeutics, USA

1 min read

Business & Regulation Regulation & Standards Business & Trends

Crisis-Ready: Building a Resilient Supply

February 2, 2021

How can European pharma better prepare for future emergencies?

1 min read

Crisis-Ready: Building a Resilient Supply

Business & Regulation Regulation & Standards Business & Trends

Vaccine Wars: EU Member States Given Power to Block Certain Vaccine Exports

February 1, 2021

New EU “transparency” measures give member states the power to block vaccine exports if manufacturers can’t meet contractual obligations

1 min read

Vaccine Wars: EU Member States Given Power to Block Certain Vaccine Exports

Business & Regulation Outsourcing Formulation Drug Delivery

Keeping Your Nose in Front

February 1, 2021

With the right partner to help you harness the many benefits, nasal delivery is not to be sniffed at

1 min read

Discovery & Development Cell & Gene

Paralyzed Mice Walk Again

January 26, 2021

Mice with severed spinal cords walk again after gene therapy

1 min read

Discovery & Development

Better Methods for Better Vaccines

January 18, 2021

When it comes to virus and viral protein analysis, settling for “gold-standard methods” isn’t good enough. To navigate the roadblocks ahead of successful vaccine development, we must dig deep into the analytical armamentarium

1 min read

February 2021

Leadership in Times of Crisis

COVID-19: A Year of Unprecedented Change

How to Standardize Advanced Therapy Manufacture

Painting the Future of Drug Delivery

Big Pharma: Heal Thyself

Are You a Bio-Catalytic Converter?

Crossing the Border

The Inhalation Advantage

Capturing Value in Changing Times

Of Plumbing and Poetry

Crisis-Ready: Building a Resilient Supply

Vaccine Wars: EU Member States Given Power to Block Certain Vaccine Exports

Keeping Your Nose in Front

Paralyzed Mice Walk Again

Better Methods for Better Vaccines

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