January 2018

January 2018

Welcome to the January issue. Upfront investigates a half-century-old “bet hedging” hypothesis, which explains the effectiveness of many common cancer drug combinations. Simon Pearce says we need to explore the chemical space outside of Lipinski’s five rules in “In My View.” Our cover navigates the trends and challenges affecting pharma manufacturing with the help of three gurus. In Best Practice, we explore the importance of sharing negative trial results; and in Profession, Annalisa Jenkins tells the story of her career, which spans the British Navy and pharma boardrooms worldwide. We also Sit Down With Tony van Bijleveld from Thermo Fisher Scientific.

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