
Catherine Bollard
President, International Society of Cellular Therapy, and Professor of Paediatrics, Children’s National Medical Centre Passion
President, International Society of Cellular Therapy, and Professor of Paediatrics, Children’s National Medical Centre Passion
Passion
“I always knew I wanted to pursue a career in Medicine, but I was also told at age 15 that I had a uniquely dramatic soprano singing voice. At 18 I was awarded a scholarship to pursue a career in singing in Australia and was accepted to Medical School. I was very conflicted, but decided to go to Medical School and make my decision after completing my medical degree. I eventually made the very difficult decision to set aside a career in music – which I have never regretted.”
Pivotal moment
“In the 1980s, my best friend in high school, Diana, developed Hodgkin’s lymphoma. Treatment comprised multiple cycles of chemo- and radiotherapy, but finally she went into remission. Later, she was diagnosed with myelodysplastic syndrome – a direct consequence of the Hodgkin’s therapy – and died soon afterwards. It was so cruel, and it became clear to me that we needed therapies that kill malignant cells and not bystander cells. As a result, I became interested in cellular immunotherapy.
“I ended up working on Hodgkin’s by chance when I moved to Houston. We’ve now developed a T-cell therapy that gives complete remissions in over 50 percent of some patient groups, and two-year progression-free survival rates of over 90 percent in other groups.
“If Diana had been diagnosed today, her outcome would have been completely different. Hence, I would say that this move to Houston and the serendipitous moment when I was able to develop a novel and ultimately, highly successful cell therapy for the same disease my friend had been diagnosed with was truly a pivotal moment in my career.”
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